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PhD position available within the HORIZON TMA MSCA Doctoral Network “Training network for Next generation cellular screening” (NEXTSCREEN)

ICFO is offering 1 PhD-fellowship position within the HORIZON TMA MSCA Doctoral Network “Training network for Next generation cellular screening” (NEXTSCREEN) to well-qualified graduate student, who wish to obtain a doctoral degree in the research topic covered.

The successful candidate will be part of the Super-resolution Light Microscopy & Nanoscopy (SLN) Research Facility at ICFO led by Prof. Dr. Pablo Loza-Alvarez for the project “Fluidic light sheet microscopy”.

The project: “Fluidic light sheet microscopy” will bring screening with Imaging Flow Cytometry (IFC) to the next level, opening the way to clinical diagnostics, making it accessible to a large range of users, democratizing its adoption. The project will connect closer the fields of microfluidics, microfabrication, microscopy and machine learning, complementing the training of the researcher with expertise with in-vitro diagnostics. The researcher will fully exploit the capabilities of the existing IFC instruments and initiate the development of the next generation automatic and data-driven diagnosis.

Thus, in the framework of imaging flow cytometry and in the identification and characterizing of tumor biomarkers in blood derived samples, the candidate will be trained by addressing the following scientific challenges throughout the actions below:
(i) develop optical, cell manipulation and fluidics lab on chips (mm-scaled);
(ii) extend the capabilities of imaging flow cytometry with novel contrast mechanisms;
(iii) high resolution imaging at, and beyond, the diffraction limit (<100 nm);
(iv) three-dimensional label-free acquisition at high rate (>100 volumes/s).

  • Preparing biological samples for optimal imaging.
  • Developing and implementing new and advanced novel imaging instruments, based on Light Sheet Fluorescence Microscopy (LSFM).
  • Analyzing complex sets of big-data images to extract relevant information using Deep learning strategies.
  • Using processed images to design computational and mathematical.

Secondment and international collaborations: The project involves an exciting network of collaborators and will include several secondments abroad in top European institutes and companies.

For further information about NEXTSCREEN please visit: https://www.nextscreen-msca.eu/


NEXTSCREEN has received funding from the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101119729

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